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来源:毒理检验科    更新时间:2016-03-30    字体大小: 【

  美高梅手机登录毒理实验室于1997年建立,1998年与中山大学公共卫生学院共建为广东省五个一科教兴医工程重点实验室, 1999年被评为深圳市第一批医学重点实验室,2000年经过中国合格评定国家认可委员会的实验室认可。现为广东省医学重点实验室、深圳市市级重点实验室、深圳市医学重点实验室。实验室现为中国毒理学会生化与分子毒理专业委员会理事单位,广东省预防医学会卫生毒理专业委员会、深圳市预防医学会毒理学评价专业委员会挂靠单位,国家人力资源和社会保障部批准设立的博士后科研工作站,深圳市博士后革新基地。在市卫计委和美高梅手机登录的领导和支撑下,实验室已形成以博士和硕士为主体的人才梯队和科研团队,现有博士生导师2人,硕士生导师7人。实验室学科带头人庄志雄教授,现任中国毒理学会荣誉理事长,中山大学和中南大学聘任教授、博士生导师。

  实验室现拥有6000多万元可实行细胞、基因组、表基因组、蛋白质组及实验动物整体水平检测及科研的先进仪器设备,同时拥有获得广东省科学技术厅颁发的SPF级和普通级实验动物使用许可证的动物实验中心。

  实验室重点科研方向为化学污染物致机体损伤的分子机制与生物标志物、及其适应与耐受机制;食品安全性检验技艺研发及健康风险评估体系建立;化学品的毒性评价与纳米材料的生物安全性评价科研。实验室同时承担接受客户委托,对食品、化妆品、消毒剂、一次性卫生用品和化学品等产品实行毒性检测和安全性评价工作。

  近年来实验室共主理国家级、省级和市级科研立项课题80项,包括国家重点基础科研发扬筹划名目(973)子课题2项、国家自然科学基金名目17项、国家863子课题1项、中国博士后科学基金1项、卫生部课题1项、广东省自然科学基金名目8项、广东省科学技术筹划名目2项、广东省医学科研基金5项、深圳市科学技术筹划名目43项(其中重点名目6项);2003年以来分别获得国家级、省级和市级科学技术成果奖23项(其中第一完成单位19项),其中包括广东省科学技术进步奖特等奖1项(参与单位)、广东省科学技艺奖二等奖4项、中华医学科学技术奖二等奖1项、中华医学科学技术奖三等奖2项、广东省科学技艺奖三等奖2项、深圳市科学技术革新奖3项、深圳市科学技术进步奖一等奖2项、深圳市科学技术进步奖二等奖2项、深圳市科学技术进步奖三等奖2项、中国毒理学会全国优秀青年科学技术奖2项、广西壮族自治区科学技艺进步奖三等奖1项、佛山市科学技艺奖三等奖1;学术会议论文获奖20篇;获得国家发明专利授权7项;在国家级刊物上颁发学术论文425篇,在SCI收录的杂志上颁发论文87篇,参与国际会议交流论文30;主编、主译专著3部,主审教材2部,参编国家统编教材和专著14部;累计培养已结业博士科研生28名、硕士科研生52名,培养博士后6名。   

   

   

  Toxicology Laboratory of Shenzhen Center for Disease Control and Prevention

  The Toxicology Laboratory of Shenzhen Center for Disease Control and Prevention (CDC), founded in 1997, was evaluated as “Guangdong Provincial Key Laboratory of Five Prosperity Projects for medical development by Science and Education” by collaboration with the School of Public Health of Sun Yat-Sen University in 1998. The Laboratory became one of the earliest key laboratories in medicine established in Shenzhen in 1999, and was accredited by China National Accreditation Service for Conformity Assessment (CNAS) in 2000. Now the Laboratory is one of Guangdong Provincial Medical Key Laboratory and Shenzhen Key Laboratory. The Laboratory is affiliated to the Committee of Biochemistry and Molecular Toxicology, Chinese Society of Toxicology and Committee of Health Toxicology, Guangdong Provincial Preventive Medicine Association. The Laboratory was approved as an independent post-doctoral training base by the Ministry of Human Resources and Social Security, and is also an innovation base of post-doctors in Shenzhen. Under the leaders’ strong support from Health and Family Planning Commission of Shenzhen Municipality and Shenzhen CDC, the Laboratory has become a powerful team, which is mainly composed of the talents with PhD and Master Degrees. Currently, there are 2 supervisors of PhD candidate and 7 supervisors of Master candidate working at the Laboratory. Professor Zhuang Zhixiong, the academic leader of the Laboratory, is the Honorary Chairman of Chinese Society of Toxicology as well as an adjunct professor, instructor for PhD candidates of Sun Yat-Sen University and Central South University.

  Up to now, the total investment in the advanced instruments used for research in genomics, epigenomics, proteomics and in vivo experimental studies in the lab has exceeded RMB 60 million. The Laboratory owns an experimental animal centre for SPF- and ordinary-class animals accredited by Guangdong Provincial Department of Science and Technology.

  Our major research fields include the dissection of molecular mechanisms, the tolerance and adaptation mechanisms of the chemical pollutant and searching of toxicity biomarkers; the establishment of the testing technology of food safety and the risk assessment system; the assessment for toxicity of chemicals and bio-safety of nanomaterials. We are also devoted to the toxic test and safety assessment for food, cosmetics, disinfection stuff, medical materials and chemicals entrusted by the customers. 

  In the past five years, the Laboratory undertook 80 scientific research projects including 17 NSFC projects, 2 sub-projects of state “973” project, 1 State “863” Project (collaboration), 1 project from the Postdoctoral Grant of China, 1 project from Ministry of Health, 8 projects from Guangdong Natural Science Foundation, 2 project from Guangdong Provincial Science and Technology Plan; 5 projects from Guangdong Provincial Medical Research Foundation and 43 projects from Shenzhen Science and Technology Plan (including 6 key projects). Since 2003, the Laboratory has been rewarded with 23 science and technology achievement awards from the State, Guangdong Province, and Shenzhen City (19 of them awarded as the first organization) including “Guangdong Provincial Science and Technology Advancement Award, Special Class” (1), “Guangdong Provincial Science and Technology Award, Second Class” (4), “Chinese Medical Science and Technology Award, Second Class” (1), “Chinese Medical Science and Technology Award, Third Class” (2) “Guangdong Provincial Science and Technology Award, Third Class” (2); “Shenzhen Innovation Award in Science and Technology” (3); “Science and Technology Advancement Award of Shenzhen, First Class” (2); “Science and Technology Advancement Award of Shenzhen, Second Class” (2); “Science and Technology Advancement Award of Shenzhen, Third Class” (2); “National Youth Science and Technology Award from Chinese Society of Toxicity” (2); “Science and Technology Advancement Award of Guangxi Zhuang Autonomous Region, Third Class” (1); “Science and Technology Award of Foshan City, Third Class” (1); “Academic Conference Research Article Award” (20). 7 national invention patents were authorized. Totally 425 research articles were published. 87 of them were published in SCI journals and 30 were conference articles. The senior staff in the Laboratory undertook compiling, translating 3 books, proofreading 2 series of textbooks and participated in the compliance of 14 books. Ever since, the Laboratory has cultivated totally 28 PhD graduates, 52 MSc graduates as well as 6 post-doctors.

   

   

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